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Is There A Problem With Taking Trazodone With A Benzodiazepine?

Trazodone is most commonly used as a sleeping pill, although it is actually an antidepressant.  It is oftentimes paired with a benzodiazepine, such as Activan, Xanax and Valium, once its effects begin to wear off and other symptoms, such as sleeping issues, appear. If you are experiencing issues from your medications or are taking multiple medications, consider Trazodone withdrawal


A Hidden Danger

Trazodone is very calming and it does not stimulate like other antidepressants. Because of this, users may not consider it to be as addictive or hazardous as other medications. Also, because it is disguised as a sleeping pill, users may not understand its full effects on the body. Not only is it harmful to the body alone, but coupled with other drugs, such as benzodiazepines, can lead to more issues.


Interactions with Benzodiazepines

There is a big problem with taking Trazodone and a benzodiazepine because of the interaction between medications. When someone becomes dependent on a benzodiazepine, oftentimes, Trazodone is added to help with the symptoms, especially sleeping challenges. At first the pairing of medications provides users with a sense of security and can help initially, but  this only lasts a short time. 


People may experience some relief and feel that it is working, but ultimately it will stop working or lead to worsening symptoms. It may take a bit of time, but eventually the Trazodone increases the blood level of the benzodiazepine. Plus, in general, Trazodone blood levels are increased by the benzodiazepine. So, you have higher amounts in your body already.


The Effects

The combination of Trazodone and benzodiazepines can lead to several negative effects.


  • It can cause breathing issues.
  • It can lead to sleep issues.
  • It also delays your body’s awareness of becoming dependent on a benzodiazepine and recognizing that the benzodiazepines aren’t working. By the time users realize it, which will happen because that combination always stops working, now they’re addicted to two drugs that they need to taper off of. 

There Is A Better Way

If you have been taking Trazodone to help with symptoms of other medications, there is a better way to find relief. If you have become dependent on multiple medications and want to taper off in a way that is effective and comfortable, you can. With the help of medical professionals, such as at Point of Return, you can achieve lasting success in Trazodone withdrawal and other medication withdrawal.


Our benzodiazepine withdrawal treatment helps users fully taper off whatever they’re on by partnering with their doctor and our experts to create a program that can bring them lasting results. Call us at 866-605-2333 or contact us to learn more about how we can assist you in your withdrawal journey.


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