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Clomipramine Withdrawal and Tapering Help

Dr. Barry Garfinkel, the director of child and adolescent psychiatry of the Unniversity of Minnesota was sentenced to federal prison for five felonies related to research fraud involving Clomipramine (Anafranil). Our NonProfit has been helping people safely withdraw from Antidepressants for over 14 Years Contact the Prescription Drug Experts if you need help!

Tricyclic antidepressants, including Clomipramine, were among the first drugs used for depression.  Anafranil (Clomipramine) is approved by the FDA but only for the treatment of Obsessive Compulsive Disorder OCD but is used off-label for depression, panic disorder, chronic pain, enuresis (bedwetting) and trichotillomania (hair pulling) and others.  Clomipramine withdrawal symptoms can occur during gradual and particularly when abruptly stopping. Contact Us if you need help tapering Clomipramine or have question.

Click here for more information and history about Clomipramine.

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Real Results for Clomipramine Dependency

The Point of Return Program is an in-home tapering program that allows you to gradually lessen the amount of Nortriptyline while also implementing the use of all-natural, calming nutraceuticals to help ease symptoms. We eliminate Interaction items to help make Nortriptyline withdrawal more comfortable. Our physician recommended schedules allow your doctor to taper you off Nortriptyline correctly.  The success of our program over the past 14 years is due to our unmatched service and unique mentoring approach. We are the Prescription Drug Experts. Nortriptyline can be dangerous to abruptly or rapidly stop and our program is a proven, viable, low-cost option to continue living your life while tapering.  Read program FAQ page.

We are prescription drug experts that specialize Antidepressant withdrawals.

We've helped people in 76 counties and in all 50 states of the USA


This is a low cost program with proven results. So don't suffer...

I owe it all to Point of Return. Thank you for all your hard work, and your perseverance, and your blood, sweat, and tears. I can promise you, that it is all worth it! I am forever grateful, and I will never stop telling people about Point of Return. more...

Helen F., (North Carolina, USA) Amitriptyline 

Key Components of Our In Home Program

  • Skilled Experts in Prescription Drugs guiding you throughout the process
  • Professional, kind mentoring
  • Assessment at the onset to determine taper rates, potential interactions, etc.
  • *Nutraceuticals specially formulated to ease symptoms, these are utilized throughout the whole process
  • Unlike herbs and many vitamins, our nutraceuticals will not interact medications
  • Information, advice and direction
  • 24/7 discussion board with encouraging members and knowledgeable mentors
  • Email and phone access at no charge
  • Recommendations for addressing symptoms such as gut problems, headaches, pain, etc. 
  • Experienced team of committed experts with over 14 years experience
  • Every person at Point of Return has a personal story with these drugs. You are not alone.

     Call toll-free  866-605-2333  to Learn More or send us an  Email.

Side Effects May Include

abdominal cramps, agitation, anxiety, black tongue, blurred vision, breast development in males, breast enlargement, confusion, constipation, delusions, diarrhea, dilation of pupils, disorientation, dizziness, drowsiness, dry mouth, excessive or spontaneous flow of milk, excessive urination at night, fatigue, fever, fluid retention, flushing, frequent urination, hair loss, hallucinations, headache, heart attack, high or low blood pressure, high or low blood sugar, hives, impotence, inability to sleep, inability to urinate, increased or decreased sex drive, inflammation of the mouth, intestinal blockage, itching, loss of appetite, loss of coordination, nausea, nightmares, numbness, panic, perspiration, pins and needles in the arms and legs, rapid, fluttery, or irregular heartbeat, rash, reddish or purplish spots on skin, restlessness, ringing in the ears, seizures, sensitivity to light, stomach upset, strange taste, stroke, swelling of the testicles, swollen glands, tingling, tremors, vision problems, vomiting, weakness, weight gain or loss, yellow eyes and skin

Withdrawal Symptoms May Include

dry mouth , constipation, bladder problems; particular improper elimination of urine, sexual problems, blurred vision, dizziness, drowsiness, Increased heart rate, insomnia, flu-like symptoms,  arrhythmias, hyoptension, seizures, hallucinations, abnormal involuntary movements, excitement, anxiety, restlessness, insomnia, nightmares, weakness, fatigue, tremors, edema of the face and tongue, bone marrow depression

Other Names for Clomipramine Include 


Break Free Today

At Point of Return, a 501(c)3 nonprofit, we have spent the last 14 years helping people taper off Clomipramine correctly. With customized taper rates and all natural nutraceuticals, our program allows you to control your symptoms and properly come off Clomipramine, once and for all, from the comfort of your home. Read program FAQs.


" I cannot say enough good things about the entire Point of Return Team.  They have somehow found just the right balance between professionalism and compassion that people who are suffering need. " - Robin T. (California, USA)  more...

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Clomipramine history and info

Anafranil (Clomipramine) is a tricyclic antidepressant (TCA) that was developed in the early 1960s by the Swiss pharmaceutical company Geigy, known today as Novartis. Anafranil is a derivative of Imipramine, an earlier generation tricyclic.

Clomipramine has significant side effects and can be especially dangerous in overdose. Tricylics seems to block the reabsorption of Serotonin and Epinephrine back into nerve cells after the neurotransmitters are released into the synapse (a structure that permits the nerve cell to pass an electrical signal). This forces both Serotonin and Epinephrine levels higher in the brain, but prevents these critical neurotransmitters from recirculating throughout the body. Both Serotonin and Epinephrine are essential for gastrointestinal health, blood platelets, the central nervous system, cardiovascular region, respiratory system, liver, and adrenal glands.  This may explain why the side effects and withdrawal symptoms of Clomipramine are so widespread. 

Clomipramine is distributed in breast milk and nursing is not recommended while taking Clomipramine due to the congenital defect risk to the newborn. 

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*While great care has been taken in organizing and presenting the material throughout this website, please note that it is provided for informational purposes only and should not be taken as Medical Advice.

*Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support. More...