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Mirtazapine Withdrawal and Tapering Help 

"I cannot thank you enough for your wonderful support and kindness and wish you all at Point of Return continuing success in helping people worldwide to be released from the shackles of these terrible drugs. - Eileen (Mirtazepinne)

Looking for help to Get Off Mirtazapine?  Our nonprofit combines a holistic approach to symptom relief with slow rates to Wean Off Mirtazepine and expert guidance and mentoring.  We’ve been helping people Stop Mirtazapine for 15 years. Tapering off Mirtazapine is critical to control the Mirtazapine Withdrawal Symptoms that include irritability, nausea, dizziness, nightmares, insomnia, brain zaps and headaches.  Mirtazapine was synthesized in 1989 and introduced to the United States in 1996. The FDA now states, "Patients currently taking Mirtazapine should NOT discontinue treatment abruptly due to risk of discontinuation symptoms." No recommendations were provided on How to Get Off Mirtazapine which is why our nonprofit has helped people in 78 countries to Wean Off Mirtazapine properly. Easing Mirtazapine Withdrawal Symptoms through a natural, comfortable approach is the most gentle way to Come Off Mirtazapine.  We provide mentoring, unique natural nutraceuticals that not only help calm the nervous system but also augment healing.  If you need Help to Come Off Mirtazapine, Contact our Prescription Drug Experts today.

How the Program and Tapering Process Works for Mirtazepine

Our Mirtazepine Weaning Program is a slow taper that allows you to safely step down from Mirtazepine under the guidance of our Prescription Experts; your Physician and Pharmacist.  

The Pre-Taper is for Symptom Relief. You will not Wean Mirtazepine until you feel better. This is where our Advanced Nutraceuticals are critical.

Point of Return provides healthy, Drug-Free Strategies to help minimize Mirtazepine Withdrawal Symptoms to improve mental and physical well-being.

Our areas of expertise are Antidepressants, Benzodiazepines, Sleeping Pills and Painkillers on a case-by-case basis.

At-Home programs are individualized based on your situation. An assessment is done once you start which allows us to individualize your gameplan based on age; length of time on the medications; health challenges; lifestyle, stress levels; additional medications; and interactions. Don't Wean Mirtazepine alone, with with our Prescription Drug Experts.  Start on your Point of Return today!

Call us about Mirtazapine

Imagine being free of Mirtazepine Dependency

- An in-home program with skilled experts guiding you throughout the progress

- Free Assessment Upon Starting our Program (a $400 value) 

- *Nutraceuticals specially formulated to help ease Mirtazepine withdrawal symptoms, these are utilized throughout the whole process 

- Unlike herbs and many vitamins, our nutraceuticals will not interact with any medications 

-  FREE 24/7 discussion board with expert mentors and encouraging members

- Strategies for addressing symptoms 

Learn More about how our process works.

Call toll-free 866-605-2333 to Learn More or send us an Email.

We've helped people in 78 countries and in all 50 states in the USA


This is a low cost Mirtazapine withdrawal program with proven results


Vicky - Mirtazapine Withdrawal

Thank you also to the beloved mentors who selflessly volunteer their time coaching and encouraging, giving us advises and support. Without God's help and POR whom God used as an instrument, I will not be here telling my testimony of success. more...

Vicky (United Arab Emirates) Mirtazapine

Trudee - tapering off Mirtazapine

By utilizing the experienced, capable, and highly informed assistance available through Point of Return I have enabled my body, mind and spirity to recuperate. Their effective nutritional products alongside their unsurpassed support have given me a second chance. more...

Trudee (Australia) Mirtazapine

Mark - taper Mirtazapine

With the regimen of POINT OF RETURN’s treatment and a slow gradual withdrawal of the Ativan and Remeron, I was healed and drug free within a short period of time.

Thank you God for directing my web fingers to Point of Return. more..

Mark (Oklahoma) Mirtazapine

In-Home Mirtazepine Withdrawal Program

Join our Mirtazepine Tapering Program today!

Break Free Today

At Point of Return, a 501(c)3 nonprofit, we have spent the last 15 years helping people taper off antidepressants correctly. With customized withdrawal rates and all natural nutraceuticals, our program allows you to come off Mirtazapine, once and for all, from the comfort of your home.  Read program FAQs

Johnny - wean off Mirtazepine


" I can't thank Point of Return enough and the best thing is knowing there are people out there like them. That's what makes me happy.   - Johnny D. (Michigan, USA) more...

More Mirtazepine Success Stories

Thank you also to the beloved mentors who selflessly volunteer their time coaching and encouraging, giving us advise and support.

by Vicky Mirtazepine (Remeron)

I want to share my story about my experience with the anti-depressant drug Remeron (Mirtazepine) and the saving grace of God by leading me to "Point of Return" through desperate searching in the internet after failed attempt of withdrawing Remeron (Mr R) and hoping can find a solution how I can kick him out from my body in a successful way. Above all I want to thank God for being with me throughout my journey to reach to the finish line of getting the Remeron out of my body. October 2015, I had my first Anxiety Panic attack that lead me to go to ER .It was after drinking a can of Red Bull energy drink. Doctor gave me valium injection to calm me down and since then I was prescribed to take home tablet valium as necessary and from then sleep was becoming a problem due to repeated attacks of anxiety. Every time I had anxiety attacked, I was sent to ER and went home with another prescription and at this time its Alprazolam Tranquilizer to help me sleep. And instead of having a good sleep, this meds makes me wide awake and tired, dizzy and anxious. Cold turkey the Aprazolam, and for 3 days no sleep at all. Consulted my Church Pastors and Church colleagues to pray for me and almost hopeless and thought I will not be fine anymore. Things get worst and worst and any option that seems I thought could helped,  all of those I tried but no changes in my condition.I consulted one of our GP doctor and was referred to the Psychiatrist to help me with my problem of sleep and anxiety. That time I was prescribed with different antidepressant and benzo 's and those did not help my condition as my body don't agree with it and instead of becoming well, it's adding me another symptoms of depressed , lack of emotion and more insomnia. I Cold turkey all those meds and November 8, 2015, my doctor prescribed me another antidepressant Remeron (Mirtazepine). I have no choice but to take it hoping it will help me. And on the 1st night with Remeron (Mirtazepine), I had a very long night sleep. From that time I continue to take the meds although I had a very horrible side effects like more anxiety, dizziness, restlessness. After 1 year of taking Mr. R, me and my Doctor decided to withdraw and stop the meds as my symptoms and sleep already improved and to taper it for 3 months but after a week of fast taper from my last the dose of the med , I had a very awful and horrible withdrawal symptoms namely :rebound insomnia, anxiety, depressed moods, anxious thoughts, nausea, vomiting, headache .dizziness, restless leg syndrome , IBS, anemia and etc. Because of very bad withdrawal side effect, I decided to go back to my psychiatrist and he reinstated my andidepressant to lower dosage. I was very hopeless already at that time. I thought I will be forever slave with this monster Remeron (Mirtazepine). And one day, while searching for an answer in the internet hoping to find ways how I can successfully withdraw this antidepressant, finally God lead me through Point of Return website. I was inspired and hopeful after reading all the successful testimonies written in the website. And to that moment I believed from the bottom of my heart that finding the Point of Return website was God's intervention and answered prayer to my long time prayers. Praised God! Halleluiah! No doubt, me and my husband committed to register and order the Point of Return program supplements .I began to taper once again and at this time in a very very slow and gradual taper and with the Point of Return Nutrients. They are wonderful, especially the Support, it's amazing.

I was determined at this time, cleaned my diet, hydrate my body, avoid the foods which interacts my medicine that cause more symptoms and took the Point of Return supplements religiously. And 5 months later after very slow taper, I am completely drug free and my healing has truly started!!! Now I am 1 month off meds and every day I noticed I'm improving. As of now I'm finishing up with some final symptoms... Without God's help and Point of Return whom God used as an instrument, I will not be here telling my testimony of success.

Thank you also to the beloved mentors who selflessly volunteer their time coaching and encouraging, giving us advises and support , to Karole, Athena, Elisa-Ruth, and Bobby , thank you to all of you, as you are part of my journey and you gave me so much courage not to give up I pray that God will bless you and give more good health and be a blessing to more people who are still on their journey and battle to get delivered and set free from the prescription drugs. God bless us all.

Vicky M. (United Arab Emirates) - Mirtazepine (Remeron)

Following the guidance of the wonderful staff at Point of Return I can now look back on this past year in awe and give eternal thanks to God for this miracle.

by Trudee Mirtazepine (Avanza/Remeron), Ambien, Zopiclone

The 28th of April will forever be one of the most significant days of my life, and I write this testimonial on the anniversary of the day God led me to Point of Return (POR). What was meant for evil, God has turned to good because one amazing woman decided to dedicate her life to save the lives of those (mine included) who’d all but lost theirs to the destructive grip of prescription drugs.

My torment of despair weakened in the presence of the hope that came from pouring over the testimonials on the Point of Return website. And now, with a joy I thought would be denied me for the rest of my life, I willingly share mine.

I will never forget the day that light shone on the darkness that had descended over me like a permanent shroud. I wasted no time in contacting Alesandra; who quickly became my angel-my mentor-and my friend. My first email, simply entitled, “HELP!” was answered within hours and thus began my journey back to , normality, health, joy, laughter, and fulfillment.

23 years ago I was doing night shift in a nursing home. I couldn’t sleep. My blood pressure hit the roof and despite my abhorrence of drugs, I resorted to sleeping pills after all the natural remedies proved ineffective. I needed to work, and therefore I needed to sleep but the pills only gave me an average of 4 hours sleep per day. My stress levels doubled, tripled and quadrupled as financial, health, and relationship challenges got on top of me. Antidepressants were prescribed and it was a downhill slide from there.

I lost count of the many times I tried to come off the drugs. I suffered a few cold turkey withdrawals; the most traumatic one was a period of 21 days without sleep. I didn’t understand about rebound insomnia and depression then. I didn’t know that our bodies reach tolerance levels soon after ingesting the poison of prescription drugs and I had no idea that it would be virtually impossible to be drug free until I found the answer in the form of a safe, slow rehabilitation program that I could do from home. Following the guidance of the wonderful staff at Point of Return I can now look back on this past year in awe and give eternal thanks to God for this miracle.

I am now writing my story in the hope of helping others who, like me had nowhere else to turn. It may only be one small ripple in a gigantic pond, but I vowed that if I regained my freedom (which I now have) I would tell anyone who would listen. This is my prayer. That one more pebble, reinforced by the weighty words of truth and thrown into a drugged sea of despair will cause a tsunami of ripples.

Avanza (Mirtazepam/Remeron) and Lunesta (Imovane) systematically stripped me of my personality, energy, passion, clarity, health and drive and exchanged them for agoraphobia, chronic fatigue, anxiety, memory loss, brain fog, hypertension and hopelessness. This does not equate to a fair exchange in my book. Our bodies are wonderfully and fearfully made but we cause every system to shut down by resorting to the myriad of quick fixes glamorously advertised and successfully marketed around the world today.

By utilizing the experienced, capable, and highly informed assistance available through Point of Return I have enabled my body, mind and spirit to recuperate. Point of Return’s effective nutritional products alongside their unsurpassed support have given me a second chance. Alesandra, Andrea, Terry, Wendy and Rachel, you not only changed my life you gave it back to me.

Thank you from the bottom of my heart.

Trudee H. (Australia) - Avanza (Mirtazapine/Remeron), Stilnox (Ambien), Imovane (Zopliclone)

I can't thank Point of Return enough and the best thing is knowing there are people out there like them. That's what makes me happy. 

by Johnny Mirtazepine (Remeron), Klonopin, Suboxone

As I started writing this I just remembered back when I was reading these testimonials when first finding this program.   Thinking how lucky I would be if I got to that point where I could write one,  something that seemed nearly impossible at the time.  And now here I am . 

Before I get into how I was right before finding Point of Return (POR) , let me share a little about how this all started in the first place.   I was 24 years old,  very healthy, in great shape.  I was a personal trainer at a gym, very active, athletic...that was my life.    Then an accident happened while I was at the gym( In 2006), the machine I was working out on snapped and struck me on the top of the head.  Causing damage to the frontal lobe...Also snapping my head forward, crushing nerves in the back of my neck and leading to alot of nerve pain in my neck, back, other extremeties. Eventually leading to parasthesia( tingling, burning sensations) in other extremeties. Over time things kept getting worse for me, and wasn't getting any answers from doctors.  And it's not easy dealing with all of these new issues on your own, not having any idea what they are, because I've obviously never experienced any of it before.  I've been injured before, I've broken bones...but never this.   Was always used to just fighting through an injury,  would still play sports and workout with a broken arm,  broken rib, etc.   Not that I enjoyed the pain, but I just couldn't resist doing something I enjoyed so much .  However with this injury, the more I tried to do, the more I set myself back..and would just end up with new symptoms that would get worse and worse and ended up with me going to the hospital eventually to try to figure out what was going on.   But that never got me anywhere  besides being offered a different med each time.

I always resisted taking a med that a doctor wanted to put me on,  but eventually would give in to some ,  justifying it saying they know what they are doing and I don't want to feel this way anymore so let me give it a shot.  Started taking klonopin in the beginning because I was having panic attacks, lots of anxiety.   Was also taking pain killers for the pain I was in.  Then I was put on Ambien because I couldn't sleep.   And was on plenty of other meds throughout the last 3 years.  And now that I am off everything, feeling so much more clear minded..getting a bit of myself back,  I realize that most of the bad things I went through was because all of the medication I was on, it wasn't just the injury.   The pain still would have been there without meds, but they made it worse. They weakened my mind over time, making me not able to handle the pain as much .  Basically not being able to handle anything.  Any type of stress would set me off.  And that's what bothered me most because I was very strong before any of that.   I just wasn't me.  And I thought that person was gone forever because of the injury.  But that is what taking all of those pills makes you believe.  It's all false.  So if there is one thing I hope you get out of reading this is don't believe the way you are feeling now is permanent.  Don't think your situation is different and that there isn't any hope for you. Because believe me, it is the medicine making you feel that way.

 I prayed to God every day throughout the 3 years, asking for help.  I will admit there were times I was ready to give up.  When the pain got real bad, sleepless nights,  the restrictions..not being able to live..be active, etc  I would lose hope at times.  The more time that went by , the less hope I had.  It was all draining me, it was a struggle just to get out of bed and go up the stairs.  Eventually my goals got smaller and smaller.  In the beginning it was about wanting to live the life I had before again, to get completely better and be active, be the happy person I always was..then I ended up giving up on that and just hoping not to feel so sick all the time, get a couple hours of sleep, not ache and burn so much, to not feel so "crazy" all the time.  Things like that.   The worst  feeling is when I did sleep and would dream about good things happening but then wake up to reality..my never ending nightmare.   I wanted to sleep all the time, I just didn't want to think anymore.  Too much pain physically and mentally.  And that is why I was on a lot of the meds , but eventually realizing a lot of those bad thoughts, feeling achy, overall not healthy at all was because of the meds.  All of those times praying to God for help, then the times where I would get mad at Him, asking why is this happening( I think we all get to that point where we think enough is enough, why is this happening to me, when will it stop, why can't I just get my life back?  And they are all the wrong thoughts).   Because over time I was giving up , losing hope. And that is the scariest thing, losing that.  When life just didn't seem that important anymore.  I remember always thinking life is too short, didn't want to get older , wanting to enjoy every minute I could, then after going through the suffering non stop for 3 and a half years I started thinking life is too long, that I'm ready to be at peace now.   It's a scary thing.    And I had to get myself out of that mode a lot.  To keep pushing when there wasn't much left.

 And why I am saying all this right now is because I'm telling you that most of the way I was feeling was because of the meds. Yes there were plenty of things I was going through without the meds but they were making it worse, much worse.  I didn't know that before, and honestly wasn't real sure about it when starting this program either.  I read the testimonials and I tried being a bit hopeful that it was the reason I was doing so bad too, but thinking to myself my situation is different and I had a brain injury and so many other things have gone wrong . So it would take a miracle for it to work for me.  I was running on fumes at the time I found POR.  And I will never forget that day because that is when God did answer my prayers, that was my miracle.    I'm sitting here right now only 6 months later and I'm doing a lot better mentally. My mind is so much more clear now. I am getting myself back.  I am still going through a lot of pain yet handling it better now, shrugging it off and being positive. I still have a ways to go , no doubt, but the difference is I am "looking forward" to everything now.  I am excited about the future.  I see a future for me.   Each day I am getting memories back , good memories.  Before the injury I could walk outside, and just look around and be happy. Appreciate everything God has given us.  Not needing anything to go my way to be happy but just to stand there, look up at the sky and appreciate life.  I lost that during the three years.  And I am getting that back now .   The excitement to live is coming back.   I am so thankful for Alesandra, Terry, Andrea, and everyone else involved at POR.   They go above and beyond to make sure everyone gets through this as comfortable as possible,  they make sure we succeed.  Because they "know" we can if we follow the program exactly the way it is.  There is no doubt for them like there is for us when starting this.   They are on the other side, they've seen and experienced everything we have been through and know exactly what it takes to heal.   I've gone to many..many doctors over these years,  been to brain rehab , etc and nobody understands the way they do.  Nobody had the answers they had.   Nobody ever took control and layed out the steps to recovery.  I always ended up going home and just dealing with things on my own again, trying to figure out what I should listen to and what not to listen to from the doctors. Because of so many setbacks I have had by listening to them, I lost that trust.  

I can't thank Point of Return enough and the best thing is knowing there are people out there like them. That's what makes me happy. 

Johnny D. (MICHIGAN) Mirtazepine (Remeron), Klonopin, Suboxone

Thank you God for directing my web fingers to Point of Return.

by Mark Mirtazepine (Remeron), Ativan

My journey was the nightmare from Elm Street. There was no end in sight. The light at the end of the tunnel was a train.

It all started one fine afternoon in February with a doctor visit for some mild anxiety about a PVD “floater” that had developed in my left eye. I was prescribed Ativan at 1 mg in the evenings to calm my anxiety but also for sleep. After a month, I noticed that my falling asleep was becoming increasingly more difficult and raised the evening dose to 2mg. As a few weeks progressed, the 2mg of Ativan became non-effective in inducing sleep and was prescribed 10mg Ambien to take instead of Ativan but to continue to take the Ativan during the day. After a few weeks it all quit working for sleep.

Doctor then prescribed a small dosage cocktail of Mirtazepine (Remeron), Amitriptyline, and Trazadone. Idea was that each one in a small dose would cause sleepiness. At times one would work, and then another, then it was decided to take them all together before bed. If I could not fall asleep then would take the Ambien after the cocktail. Continued with 2mg of Ativan during the day. Then was put on Lexapro to take during the day because I was now depressed and anxious.

My blood pressure was now at 180. Pulse would run in the 120. Sugar was in the 140’s. A big piece of the problem was no one ever told me how addictive Ativan was and if you quit taking it---you went to a major withdrawal.

The last day of my old life in an attempt to stay sane included Ativan during the day along with Lexapro. Then for sleep—would start with the cocktail of Remeron, Trazadone and Amitriptyline about an hour before bed (varying the doses each night somewhat). That would never cause sleep—so would then at bedtime take 10 mg of Ambien. In an hour take another 10mg of Ambien. And if that did not knock me out (which in the end – it would not)—top it all off with 1 or 2mg of Ativan. Wow—what a day of pill popping---all for a little sleep.

One spectacular Saturday in August, I was researching on the Internet about how different drugs had different channels to the brain and how some did not work together—stuff way over my head—but somehow found Alesandra’s web site. I called and spoke with Terry. He told me that I really needed to speak with Alesandra and I left my number. That evening I was horribly depressed at my parents home.

About 9pm I got this phone call from Alesandra. I was amazed that someone was calling me back that late on a Saturday evening. But for 2 hours, she and I talked about everything. It was the first time in my 6 month ordeal that someone knew what I was going through and understood my problems.

I had spoken to at least 10 different shrinks, sleep counselors; etc…everyone wanted to put me on some other type of drug. Alesandra knew exactly in less than an hour how badly I was messing with my brain chemistry by taking all that crap and in different doses. My brain was being zapped daily and there was no end to it.  That evening I concluded to limit myself to a max of 3 drugs and stabilize the chemistry in my brain.

Ativan was number one—because it was the most addictive. I was given the choice of what other two I thought I needed for sleep. I decided on Remeron and Ambien. That evening, I took the Remeron at bedtime with 2 mg of Ativan and fell asleep without the Ambien. Thereafter, I never took Ambien again and with the regimen of POINT OF RETURN’s treatment and a slow gradual withdrawal of the Ativan and Mirtazepine (Remeron), I was healed and drug free within a short period of time.... that was 2 years ago.

Thank you God for directing my web fingers to Point of Return.

Mark M. (Oklahoma) Mirtazepine (Remeron), Ativan

Life for me now is just so busy with a wife, raising three teenagers, running a remodeling business and now just started a cabinet shop. Life today sure is not what it was 6 months ago or even 1, 2 or 3 years ago – as you know!!  I'm just sorry that I haven't shared my story until now.

My road to recover started at least 4 years ago when I was surfing the web one evening trying to find a way out from what the doctors were telling me. They said I would be on medications for depression and anxiety for the rest of my life! I ran onto a site called POINT OF RETURN. I started reading all the info and was very unsure of what I was reading, but I decided to call.

Andrea answered the phone and as we talked, I finally realized that you understood what I was going through better than anyone else did for the past 7 years – including my psychologist, psychiatrist, counselors, etc… It still amazes me how you picked up that I was struggling with suicide when I didn't even tell you or hint of it. Other symptoms included 20-30 panic attacks a day, weight gain that I couldn't loose, swelling and on and on. 

God used you to save my life in more ways than one. The doctors had me so drugged up, that I felt like a robot with no emotion or feeling. Once I started the program, I gradually started to fell better. The thoughts of suicide began to leave. Within 4 months, I was off the antidepressant medication (REMERON). The Klonopin was a lot slower. It was so neat to hear my wife say, "Wow, you are beginning to care about me and the kids again and life in general!"  Taste, hearing, smell, sight – all started to return. One year later, I was able to get off of disability after 7 long years. Today, May 1-, 2009; things are great compared to what they were!!!  Does that mean no problems? NO, but I have no thoughts of suicide for years now, I had only one panic attack in 4-6 months, my energy is great – even when I only get 4-5 hours of sleep. Before I slept 8 – 10 hours or more and still couldn't get going. I have no more swelling; my weight was around 210 – 220, now I'm 160 – 170.

I have a Christian band called Prepare the Way. Before to get up to perform in front of an audience was torture with panic attacks - now I'm just a little nervous with the ability to control it and I started to enjoy performing.

The most important thing of all is, that God helped me every step of the way. He used Andrea and others to help me. Thank you Andrea and everyone at POINT OF RETURN from me, my wife Debbie, Tim, Austin & Faith. We love you all!!!!

Wayne S. (Arkansas) - Mirtazepine (Remeron), Klonopin

Hi, my name is Graham, from Ireland, and I've struggled with depression for many years. I have spent time in different countries around Europe, the Middle East and Africa and had occassion to visit doctors in all 4 countries, with the result of having many different drugs prescribed over the past 15 years (Prozac, Xanax, Mirtazipine, Fluoxetine and others I forget!). I eventually was put on Zispin (Mirtazipine) for the past 4 years and was told I could never and should never come off them. However, over the past years I noticed and grew to be concerned over many of the side effects, also the doctor wanted me to come off 'for a break' as my white blood cell count went too low. So, in June of this year my GP prescribed strange way to taper and it did not suit my body and mind, so I thought it right to go back on the main dose...but before I did, I found Point of Return on the internet and wrote to Alessandra telling her of my concerns about tapering. She promptly and kindly emailed me her thoughts/experiences on the matter and I just couldn't bring myself to take the step and commit to a proper taper schedule. It was fear that was holding me back. Fear of failure, fear I couldn't function without my drugs, fear the depression would return...fear is a terrible thing, it holds so many people back from becoming the person they really are. I eventually took the plunge and have successfully tapered off Zispin and during taper I experienced very little symptoms/side effects. It was NO WAY as scary a process as I had built myself up to 'fear'. I'm delighted to have come off the medication and have felt much better as a result...clarity of thought, memory function and generally feeling 'normal' at last...after so many years. I hope this will help you make a more informed decision - take the risk...it's well worth it!

I wish you well...

Graham W. (Ireland) - Mirtazepine (Zispin/Remeron)

I appreciated the warmth and kindness of the POINT OF RETURN staff and the promptness of their replies.  Withdrawal can put you in a fragile and vulnerable place and they understand that.

by Nancy Mirtazepine (Remeron)

My story began 14 years ago when my husband and I moved our family to Eastern Europe to do Missionary Work.  It seemed immediately upon my arrival I started struggling with Insomnia.  I consulted an American Doctor who was there in the same country working to set up a medical clinic.  She recommended several drugs that I took for a time, but none of them seemed to help.  The medicines available in this country at that time were limited and older medications and they were all available over the counter. If you knew the name of the drug you wanted you just went to the pharmacy and purchased it, no prescription was necessary.  I tried Valium and Amitriptyline.  Neither of them worked very well.  They seemed to slow my heart and cause me to want to sleep all day.  But I never felt rested, just drugged.  After a couple of years without a solution, I felt I needed to return to the states to see a Doctor and try to get at the bottom of this problem.  I felt there had to be an answer. 

When I saw the Doctor I tried to explain some of the factors that I thought were contributing to my insomnia or were possibly at the root of it.  He said that he didn't need to know all that.  He proceeded to give me a prescription and said if this one medication didn't work he had several we could try and for sure one of them would work.  The one that he thought might be best was a newer medication called Mirtazepine (Remeron). 

I returned overseas and things began to smooth out for me.  It seemed that the prescription worked like magic.   I realized that I did experience some side effects but they were not as bad as the insomnia so I over looked them.  Because of our lifestyle of living overseas we would return to the states every 2 years and then for just the summer.  I would bring a years supply of my medication back with me and then in the off year I would have someone bring it over to me. 

I had been on Mirtazepine (Remeron) for about 7 years, when I began to have problems.  It began in the fall of 2003 about a month after I had started a new prescription.  It was a generic form of Mirtazepine (Remeron). This was the first time I had taken Mirtazepine (Remeron) in generic.  I started having a nightly recurrence of insomnia, usually a gap of about 3 hours.  Since we were still overseas I went back to the American Doctor who had helped me before.  She had been prescribing my Remeron recently and was my closest link to help.  She recommended that I increase the dosage to see if that would help.  We worked together for 4 months trying to resolve the insomnia but to no avail.  Finally in February 2004, out  of frustration,  she suggested that I stop taking the Remeron altogether.  I questioned her, "You mean like just stop it tomorrow?" She said,  "Yes.  It isn't working and besides it will be out of your system in a week."

That was when my nightmare began.  I was fine for several days and then about day 4 my body went berserk.  I was working in our apartment one minute, and the next moment I threw open our front door and was running barefoot downstairs.  I don't know what came over me.  I didn't know what I was doing.  I ran to a neighbor's apartment.  My heart was beating very rapidly and I was having trouble speaking.  Something was really wrong.   She called the American Doctor who said to get a dosage of Remeron back into my body immediately.  We began a process over the next days of trying to get this chemical back into my system as quickly and safely as possible to counteract the withdrawal effects. 

I went back on the Remeron but that didn't seem to be much of a solution.  My body was reeling from the abrupt stopping and starting of the drug.  Because of the abrupt withdrawal I now had a host of other problems.  Not the least of which was heart racing, seizures, panic, depression, anxiety, brain zaps, paranoia etc. I was terrified.  My life had been turned upside down and I was trying to hang on. It was recommended I take new medications to control the withdrawal symptoms.  They included beta-blockers for the heart racing, anti seizure medicine, Ambien for sleep, other antidepressants, and Xanax for panic.  Over all I ended up taking at least 8 different medicines to try to fix the withdrawal symptoms.  All I knew was that I wanted off this Remeron.  I knew it was no longer working and now I had a whole host of other problems.

At this point my American Doctor came up with a 6 week taper.  It didn't seem like things could get worse but going completely off of Remeron again intensified everything. I started having trouble functioning.  I was trying to hang in there as I was just 2 months away from my oldest son's High School graduation in June and then we would be going back to the states as a family.  About a month before graduation, it became apparent that I needed medical intervention beyond what I could receive where I was living.  I was so sick and fragile that waiting was not an option.   I love to travel and had made many trips by myself, but this time was different.  I couldn't travel alone. God provided a friend who escorted me home for the 15-hour journey to the states.  I don't remember much about the trip only that I cried most of it.  I just remember people staring and all I could do was cry.

I entered an inpatient program at a counseling center.  I saw counselors every day Monday through Friday, sometimes several times a day.  I saw medical Doctors and a Psychiatrist.  Not much was getting any better.  I felt so strange, like I was losing touch with reality.  I began to feel like everything was closing in on me.  I couldn't be in a room with a closed door and whenever I was in my apartment I had to keep the doors open.  I started having suicidal thoughts also.  When I voiced these feelings to the counselor, they insisted I had to go back on the Mirtazepine (Remeron).  They told me that all of these symptoms were telling me that I needed to be on this medicine.  I was too confused to argue.
So after 9 months of hell and stopping and starting Remeron twice, I found myself back on it again.  Because my health had taken such a beating and I was emotionally fragile we felt that we should resign our post overseas.  We were reeling from the ordeal.  We spent the next year just trying to put the pieces back together.  It took me that long to get some semblance of normality back in my body.  I had so many questions.  What had happened to me?  What went wrong?  It would be 4 more years on Remeron before I had my answers.

In that time I tried to quit Mirtazepine (Remeron) on my own several times.  I had researched information and understood that my previous withdrawal attempts had been too rapid and that I needed to withdraw more slowly.  I would try to cut pills and this didn't seem to work.  I couldn't seem to get them uniform.  I even tried to cut pills and then came up with an elaborate schedule of my own taper.  On alternating nights I would reduce the dosage by cutting pills.  My idea was to do it slowly and consistently.  This too did not work.

I began to resign myself to the idea that I was stuck on this medicine.  This medicine controlled my life and I knew without God's intervention if I ever got separated from my medicine for more than a few days that I most likely wouldn't survive.

In December things were going along normally when I began to experience withdrawal symptoms again.  I thought what is going on? I am not trying to withdraw.  I remembered when I picked up my prescription I noticed it was cheaper than usual.  I went to the bottle and sure enough my Pharmacy had switched manufacturers.  I thought this is crazy.  I felt so vulnerable.  How could some generics work for me, and others not work and throw me into withdrawal!  I was scared.  As I thought about it I wondered if this could have been the same manufacturer that produced the Generic Remeron that began all my problems in the Fall of 2003?

Now more than anything I wanted a way out, but I didn't see an imminent solution….

But GOD….

In September while at our public library getting books for a trip my husband was taking, I noticed they had a bin of magazines with a sign "Free."  I don't usually have time to read magazines but some of them had never been opened and were still in the plastic mailer.  I grabbed a couple thinking while my husband was gone I would have time to look at them.  Several nights later I picked one up to look at an article advertised on front about exercise when my eyes landed on an article entitled "Are Generic
Drugs Safe?" (Prevention Magazine Feb. 2008).   As I read the article I was stunned to realize that what I had thought possibly had caused my problems I now believed to be the source.  Generic medicines are not monitored, as they should be.  They are often not as strong or potent as the name brand drug.  As I read I became convinced that this was why I experienced withdrawal and the host of other problems that escalated from the generic drug.  Even though I had suspected it, to have it confirmed in my hands in print after so many years was sobering.

After reading the article I thought what do I do?  I initially thought that I just needed to get back on the name brand of the drug, but when I researched it and realized how expensive it was I thought this isn't my solution.  I would still be a slave to this drug.  I continued to research everything I could on the Internet about Remeron and drug withdrawal.  I came across several posts where people said taking Remeron was very similar to smoking marijuana.  This was sobering to me as I have 2 sons who had been arrested in the past year for possession of Marijuana.  I know we are each responsible for our own actions.  However, if there was any connection between Remeron and marijuana I did have to wonder if my addiction to a legal drug had opened a door for them to abuse an illegal one.  I didn't want there to be any kind of link for them to use drugs, legal or otherwise.  I knew at that point that no matter what the outcome I had to get free.

In that process God directed me to the POINT OF RETURN website.  I sat mesmerized by the testimonials.  I couldn't believe that I wasn't alone.  I called my husband who was 3,000 miles away and shared with him how God had spoken through the magazine article and the research.  I cried as I spoke with him.  God hadn't forgotten me and was making a way for my freedom and healing.

I began the POINT OF RETURN Withdrawal Program in October and finished it in March.  I followed it religiously.  The supplements really worked.  I had some side effects but the protocols in the manual were my guide and I adjusted things as issues came up.  I appreciated the warmth and kindness of the POINT OF RETURN staff and the promptness of their replies.  Withdrawal can put you in a fragile and vulnerable place and they understand that.

Knowing they were just a phone call or email away gave me such confidence.  For the most part of the program I didn't need any extra assistance.  Since finishing the taper I have had some insomnia and I have emailed Alesandra.  She has given me some suggestions.  I have so appreciated her kindness and support.  She is helping me over some rough spots with insomnia and her encouragement has been invaluable.

I know that my body is still healing.  Withdrawal is a process that doesn't just end after you take your last dosage.   After 12 years on the medication it will take some time to heal but the worst is past.

I am grateful to God for His provision and help in this process and for leading me to the POR program.  What the enemy of my soul has meant for evil, God will take and use for Good.

I love what author Graham Cooke has to say, "Father, Thank You for favor and vengeance combined.  That, in our freedom in Christ, You not only deliver us from being victims but You give us a ministry in the very area where we have been robbed and ashamed.  Everyone that we in turn set free is a sign of our payback on the enemy.  To destroy the works of the devil is the evidence of Your power at work."

Bless You!!

Nancy R. (California) Remeron

Dear Alesandra – Vitality, Enthusiasm for Life, Energy and Joy – thanks to your wonderful Organization. I have recovered my zest for life after a very short time of following your Program and taking the wonderful all-natural products.  Four months ago, when I was experiencing depressive symptoms and writing suicide notes due to the side effects of ZOLPIDEM (AMBIEN) the sleeping medication to which I had become addicted and tolerant, I was only getting 2 hours of  sleep per night.  I ended up in a psychiatric hospital where I was given MIRTAZIPINE (REMERON).  I was already aware of the warnings on this drug and as soon as I was discharged, I withdrew too abruptly from both drugs – I now know  from your literature that ‘tapering’ would have been a safer option. This led to very unpleasant withdrawal;  nausea, panic, disturbed sleep, loss of feelings in my legs below the knees and extreme fatigue.  It was at this point that I found your website POINT OF RETURN.  I knew my prayers had been answered when I phoned and heard your voice of encouragement Alesandra.  I instantly knew that I would find my way back.  Your comforting words gave me hope and confidence.

Within 3 days of commencing the Program, the feelings had started to return in my legs and the nausea and panic had subsided.  The fatigue lasted a little longer but each day I noticed a difference which gave me so much hope.   Now I have the energy to engage with my 4 grandchildren, walk and play 18 holes of golf and have resumed my professional working life in a part time capacity and all this within 4 weeks of using the supplements.  I now wake after wonderful restorative sleep each night ready to face the next day.

I cannot thank you enough for your wonderful support and kindness and wish you all at POINT OF RETURN continuing success in helping people worldwide to be released from the shackles of these terrible drugs.   Yours very sincerely,

Eileen, (UNITED KINGDOM) - Mirtazapine (Remeron), Zolpidem (Ambien)

Today I am free of drugs. Free from Xanax which was causing me more Anxiety, Tramadol that caused more pain, Mirtazapine and Effexor.

by Laura Mirtazepine, Effexor, Xanax, Tramadol

Thirty years ago may have been the beginning of a down-hill spiral for me when I was put on antidepressants for a persistent nerve pain in my arms and hands. Amazingly they did stop the pain and because of my trust in our medical Dr./friend I thought I'd need this drug for rest of my life to correct the diagnosed chemical imbalance.

While on the Imipramine I had mood swings, dry mouth and a nightly three hour ritual of twitching and jerking. It was the end of the blissful deep sleep I had once known. Relocating to another state meant changing to another doctor and then another and another as I became discouraged with their inability to make me feel better. The first and only effort ever made with each new doctor was to change my antidepressant. I even had the degrading experience of a homeopathic Dr. tell me there wasn't anything more they could to for me. "O.K. what is wrong with me? I don't feel well. Am I going to wither up and die for no reason at all? Oh, yes, I have Fibromyalgia. It's causing the tiredness, muscle pain, acid reflux and sleep disorder.

Oh, thank goodness. My joins are wearing out. Now there is a real reason for the pain. The five joint replacements have been helpful but the diseased spine is still hard to deal with. The spinal injections haven't helped so I really don't know what to do next. Suffer and live with it I suppose. At this rate I may not want to see 70.

Five children and their spouses, fourteen grand children all live a thousand miles away and seldom come to visit. They are too busy with their own lives so I am doomed to die lonely in some facility because my husband won't be able to care for me as my mental and physical health diminish. They will keep me calm and quiet for a few years until I slip away."

GOD BLESS MY DAUGHTER, BARBIE, who so tenderly and cautiously questioned me about my antidepressants. "Mom, I have a friend who was really sick and taking several drugs but now she is off of them and she has a whole new life." "But I still have the pain and the Dr. said I have a chemical imbalance.
I can't hardly ride in the car because the vibrations hurts me so bad. Dad does all of the housework and shopping." "Would you mind if my friend e-mailed or called you? "No, I don't' mind. I can listen or not listen."

That was the beginning of my journey to healing with POINT OF RETURN and my, now dear and precious, friend Alesandra. It has been one year this month of September since I began the program and today I am free of drugs. Free from Xanax which was causing me more Anxiety, Tramadol that caused more pain, Mirtazapine and Effexor. Even my stomach is healing and I have stopped the purple pill.

It hasn't been a bed or roses. It was hardest on my dear husband of 48 years. He is a saint you know. We are acting silly again just as we did years ago and we are still very much in love at the age of 66 and 70.

We hope to shorten the miles between us and our family by traveling more frequently. We have been blessed with a Great Granddaughter and we have yet to see and spoil her just a little. We just returned from Arizona where we reunited with two friends we had not seen or heard from in thirty years.

My grandchildren thought it was amazing to see photos of me (grandma) on a recent camping trip, standing up to the waist in a stream of water and fly fishing for trout. I'm a tough cookie sometimes and stubborn (they say) but I didn't know what a fighter I was until now that I look back on this past year and
realize that I never once thought about quitting the program.

Could it have something to do with Alesandra Rain, the program itself, the prayers I didn't know about. Yes, all of the above and more. I am dead set against the misuse of drugs and have always made a strong and lasting impression upon our children pertaining to them. For me to think that I was addicted to prescriptions drugs never entered my mind and would have horrified me.

Pain is no stranger to me so I am more compassionate to those who suffer than I use to be. I want to say clearly that I don't believe a laboratory cocktail of chemicals, compressed into a tiny pill, are natural to the human body and they are definitely not the answer to a healthy mind and body.

Laura S., (Colorado) - Xanax, Mirtazapine, Effexor, Tramadol

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Mirtazepine Withdrawal Symptoms May Include

aggression, anxiety, balance issues , blurred vision, brain zaps, concentration impairment, constipation, crying spells, depersonalization, diarrhea, dizziness. electric shock sensations, fatigue, flatulence, flu-like symptoms, hallucinations, hostility, highly emotional, indigestion, irritability, impaired speech, insomnia, jumpy nerves, lack of coordination, lethargy, migraine headaches / increased headaches, nausea, nervousness, over-reacting to situations, paranoia, repetitive thoughts or songs, sensory & sleep disturbances, severe internal restlessness (akathisia), stomach cramps, tremors, tinnitus (ear ringing or buzzing), tingling sensations, troubling thoughts, visual hallucinations / illusions, vivid dreams, speech or visual changes, worsened depression

Mirtazepine Side Effects May Include

Abdominal pain, Chills, Fever, Face Edema, Ulcer, Neck rigidity, Neck pain, Chest pain, Hypertension, Angina, Migraine, Goiter, Hypothyroidism, Thirst or dehydration, Weight loss, Abnormal healing, Diabetes, Arthritis or bursitis, Anxiety, Agitation, Twitching, Hostility, Reflexes increased, Convulsions, Sinusitis, Cough increased, Rash, Acne, Urinary retention


Other names for Mirtazapine Include

Avanza, Remeron, Zispin, Norset, Rexer, Remergil, Mirtabene, Remergon, Mirtazon, Axit, Mirtaz, Promyrtil, Noxibel, Mirzaten and Mizapin Sol

Mirtazapine history and info

A massive 2014 study of 22,610 people analyzed the affect on weight from the use of antidepressants. Mirtazapine (Remeron) was found to cause the greatest amount of weight gain, representing a 7% increase per year.There have been many reports of withdrawal symptoms upon the discontinuation of Mirtazapine or with a too rapid titration.

The FDA states, "Patients currently taking Mirtazapine (Remeron) should NOT discontinue treatment abruptly, due to risk of discontinuation symptoms. At the time that a medical decision is made to discontinue treatment with Remeron (Mirtazapine), a gradual reduction in the dose, rather than an abrupt cessation, is recommended."

Remeron (Mirtazapine) was introduced in the United States by the Dutch firm Organon International in 1996. Organon's first product was insulin in the 1920s and in the 30s they manufactured estrogens. Scherring-Plough Corporation acquired Organon in 2007, and in 2009 they was merged with Merck Pharmaceuticals. In October 2014 the U.S. government charged the manufacturer of Remeron with making improper financial incentives (kickbacks) to nursing homes to encourage the use of their drug. They were also charged with misrepresentation of drug prices and ordered to pay restitution for breaking the Federal Anti-Kickback Statute.

Mirtazapine is known as a Tetracyclic antidepressant and classified as a Noradrenergic and Specific Serotonergic Antidepressant (NaSSA), meaning Mirtazapine affects Norepinephrine and Serotonin.

Mirtazapine increases the release of both Serotonin and to a lesser degree Norepinephrine (Noradrenaline). Norepinephrine increases blood pressure, affects parts of the brain where attention and action is controlled. Along with Epinephrine, Norepinephrine creates the fight-or-flight response that increases heart rate and triggers the release of glucose while increasing blood flow to the skeletal muscle. Serotonin influences the cardiovascular, renal, immune and gastrointestinal systems, and is essential to regulate body temperature, heart rate, blood pressure and the sympathetic nervous system. Mirtazapine is also a potent antihistamine that contributes to its sedative qualities but is also known to cause weight gain and sugar cravings.


according to the FDA, Remeron can cause the following symptoms:

Nervous System: frequent: hypesthesia, apathy, depression, hypokinesia, vertigo, twitching, agitation, anxiety, amnesia, hyperkinesia, paresthesia; infrequent: ataxia, delirium, delusions, depersonalization, dyskinesia, extrapyramidal syndrome, libido increased, coordination abnormal, dysarthria, hallucinations, manic reaction, neurosis, dystonia, hostility, reflexes increased, emotional lability, euphoria, paranoid reaction; rare: aphasia, nystagmus, akathisia, stupor, dementia, diplopia, drug dependence, paralysis, grand mal convulsion, hypotonia, myoclonus, psychotic depression, withdrawal syndrome.






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*While great care has been taken in organizing and presenting the material throughout this website, please note that it is provided for informational purposes only and should not be taken as Medical Advice.

*The statements on this website have not been evaluated by the Food and Drug Administration (FDA). The products and labels mentioned / sold are not intended to diagnose, treat, cure, or prevent any disease or illness.

* Testimonial results may vary person to person.

*The program outlined in Point of Return is not meant to substitute your doctor, instead it is to be utilized with your physician to help you with your drug withdrawal process and with his or her consent.

*Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support. More...