Omega 3 fatty acids are considered essential for human health and are contained in fish, some nuts, seeds and through purified supplements. Omega 3 fish oil contains both docosahexaenoic acid (DHA), the main fat of the human brain; and eicosapentaenoic acid (EPA). DHA and EPA may reduce the risk of hypertension and coronary heart disease.
Health Benefits of Omega-3's
DHA is the main omega-3 fat in your brain and essential for a functional nervous system, which includes your brain. DHA is linked to improved heart health, better vision and reduced inflammation. DHA is naturally
produced in small quantities in our bodies and to achieve adequate amounts it must be ingested through dietary sources.
DHA may be more effective than EPA in improving your Omega 3 index, decreasing bad cholesterol while improving your cholesterol profile. DHA supports good blood flow (circulation) that may improve the ability of your blood vessels to
dilate (endothelial function). DHA reduces the entry of enlarged LDL particles into the muscle cells that line the arteries, reducing the likelihood of atherosclerotic lesions, helping reduce heart attacks and stroke risk.
Studies have shown that people with Alzheimer's disease have lower levels of DHA in their brain.
EPA primary function is to lower inflammation, but has been shown to help with conditions such as asthma, menstrual problems, hot flashes, lung diseases, lupus or other immune reactions.
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Triglycerides vs Ethyl Esters
Fish Oil, docosahexaenoic acid (DHA) and eicosapantaonic acid (EPA) are available in two forms: Triglycerides or Ethyl Esters. Why does Point of Return only use Triglycerides versus Ethyl Ester? Fish are inherently Triglyceride and Ethel Esters do not appear in nature.
So which form are the long-chain Omega 3 fatty acids (DHA and EPA) that we absorb when eating fish? The answer is Triglyceride since over 98% of all fats are in Trigylceride form.
Cost vs Absorption
Ethyl Ester Omega 3 fatty acids are prevalent in the market due to cost: they are cheaper to produce than Triglyceride forms. Studies have shown that Ethyl Esters are the least bio-available forms of Omega 3s compared to Triglyceride forms.
Check labels! We are proud of our Triglyceride (TG) formula and unless its stated on the label it is Ethyl Ester.
Comparing Fish Oils
When it comes to omega-3, what is important is what the gelcap actually contains. For example, a average 1,000 mg fish oil capsule might contain 200-400 mg of omega-3s but also 600-800 mg of other saturated and unsaturated fats per
capsule – fats that actually interfere with the efficacy of the health providing omega-3s DHA and EPA. The higher purity and greater concentration of MOOD means you're getting the maximum omega-3 benefit possible.
The low temperatures used in Supercritical Extraction Technology ensures the maintenance of the oil's molecular integrity. During this state-of-the-art process, the oil is extracted under a nitrogen blanket to ensure the oil stays fresh throughout the process by preventing the oil from being oxidized.
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Supercritical Comparison Chart
|Supercritical Technology||Molecular Distillation||Liquid Chromatography|
|Use of organic solvents||NO||NO||YES|
|Risk of end product contamination||NO||NO||YES|
|Risk of product degradation due to oxygen exposure and use of high temperatures||NO||YES||NO|
|Risk of unwanted oxygen exposure and oxidation||very low probability||probable||possible|
|Efficiency in eliminating contaminants (heavy metals, pcb's, dioxines & others)||
almost total or undetectable levels
almost total or undetectable levels
|Sufficient molecular separation to obtain high and very pure EPA & DHA concentrates||
Maximum concentration (+90%) and purity of EPA & DHA
when concentrated with Urea in EE form no separation of EPA & DHA
85 - 90%
Scientific Explanation of Triglycerides vs Ethyl Esters
EPA and DHA provided in the natural triglyceride form of fish oil have different properties than those of Ethyl Ester. Both Triglycerides and ethyl esters are considered 'esterified' meaning that an ester link holds the fatty acid into
their chemical backbone. The fatty acids in triglycerides are esterified to a glycerol backbone - the fatty acids in ethyl esters are esterified to an alcohol backbone of ethanol. This difference is dramatic.
Baileys Industrial Oil and Fat Products state "Fatty acids in oils and fats are found only esterified to glycerol." This definition in an industry standard reference book on food chemistry and processing technology relates to edible
oils, and ethyl esters are not technically oils. Labeling ethyl esters forms of fish oil is legally allowed yet technically inaccurate.
Triglycerides, which contain three fatty acids attached to a glycerol backbone meet the definition of a true oil.
Evidence suggests that TG fish oils are more readily absorbed than EEs, and clinical evidence indicates that Omega 3 benefits are directly related to fish consumption. Fish are naturally in the TG form, while there are no EEs in nature. Ethyl Esters have been in the food chain for about 20 years whereas Triglyceride Fatty Acids have been providing benefit for thousands of years.
That are Triglycerides?
Trigylcerides (TG) are found naturally in fish. It’s the most natural version of fish oil but expensive to extract and process as they are more delicate. Triglycerides are the fatty acids (DHA, EPA) that are attached to a glycerol backbone. This is the molecular form that is in both animal and plant species. The Omega 3 fatty acids present naturally in fish are exclusively triglycerides.
What are Ethyl Esters?
Many Ethyl Esters are produced through a process that combines crude fish oil in a free fatty acid form with ethanol (an industrial alcohol) to form a synthetic substrate. Under a vacuum, the mix is then heat distilled to create a concentrated ethyl ester solution.
Ethyl esters are comprised of one fatty acid attached to one ethanol molecule and are not found in nature, but are created through chemical synthesis. The body must attempt to convert the Ethyl Esters to Triglycerides to use it. Many do this conversion
Ethyl Esters are cheaper to produce than Triglycerides. Many Ethyl Esters are brought to high temperatures making them more malleable for easy production. However, when Ethyl Esters are consumed, they must be processed in the liver where the ethanol is removed, than the body must rebuild the free fatty acids back into a Triglyceride. This inefficiency not only delays the Omega 3s to the bloodstream, but the release of ethyl alcohol may subsequently produce oxidative stress by releasing free radicals.
- Omega-3 fatty acids and pregnancy
- Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression.
- Animal Study Suggests Omega-3 Lessens Depression, Mania
- Essential fatty acids, DHA and human brain
- Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity.
- The salutary effects of DHA dietary supplementation on cognition, neuroplasticity, and membrane homeostasis after brain trauma.
- Maternal DHA equilibrium during pregnancy and lactation is reached at an erythrocyte DHA content of 8 g/100 g fatty acids.
- Long chain omega 3 polyunsaturated fatty acids supplementation in the treatment of elderly depression: effects on depressive symptoms, on phospholipids fatty acids profile and on health-related quality of life.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, prevent or cure disease or illness.
*Always consult with your healthcare professional before starting any diet, exercise or supplementation program, before taking or stopping any medication, or if you have or suspect you might have any health problem. More...