There are no side effects from RELAX, only the ability to regulate the perception of stress. Relax will not prevent an individual from evaluating the importance of a situation as some medications can.
Relax is a virtually lactose-free natural protein containing a bioactive decapeptide that has clinically proven anti-stress properties to help with tension. Studies have shown that this 10-amino-acid peptide is derived from natural origins and is free of undesirable side effects, issues of tolerance or addiction.
Stress is a state where internal and/or external forces increase tension. Medications, alcohol and smoking can worsen anxiety and make the body more sensitive to tension. Stress releases powerful neurochemicals and hormones that cause the heart to pump harder, breathing to increase and muscles to tense in preparation to take action.
One of the dominant hormones released during times of stress is Cortisol. Although Cortisol is an important hormone involved in glucose metabolism, blood pressure regulation, insulin release for blood sugar maintenance, immune function and the inflammatory response, it also activates the relaxation response so the body’s functions can return to normal.
But prolonged levels of Cortisol can cause negative effects that include: Impaired cognitive performance, blood sugar imbalances, decreased bone density, decrease in muscle tissue, suppressed thyroid function, higher blood pressure, lowered immunity, poor inflammatory response in the body, and increased abdominal fat.
Additionally, there is a close relationship between Cortisol and Melatonin, the sleep-regulating hormone. Melatonin and Cortisol are designed to run opposite to each other. Cortisol levels should be high in the morning and reach their lowest point at bedtime, whereas Melatonin levels peak a few hours after Cortisol levels drop and decrease by morning. Sustained high levels of Cortisol interfere with the natural sleep patterns by reducing Melatonin production. Over-the-counter pain relievers, sleeping pills, anti-anxiety medications and some antidepressants can interfere with Melatonin secretion at night, thus increasing Cortisol levels.
Prolonged use of Selective Serotonin Reuptake Inhibitors (SSRIs) elevate Serotonin levels which cause the adrenal glands to release both Cortisol and Adrenaline (Epinephrine) to combat the excessive Serotonin. This initial calming gives the impression that boosting Serotonin is pleasant. However, over a prolonged period of time the adrenal glands may lose their efficiency and “Adrenal Exhaustion” can occur, with adrenaline levels dropping and Cortisol levels rising. Eventually, even Cortisol levels fall and this may help to explain why so many antidepressant users eventually experience extreme fatigue.
Cortisol release is regulated by our circadian rhythms (24-hour sleep/wake cycle), with levels the highest in the dawn hours, which coincide with the time that melatonin levels begin to dramatically decline. There is a balance between Cortisol levels and Melatonin; one is high when the other low and this dance helps to regulate the sleep/wake cycle. Benzodiazepines and Sleeping Pills can suppress
Melatonin production and interfere with nocturnal secretion, which in turn affects Cortisol. High levels of Cortisol at night can result in difficulty falling or staying asleep and in turn can cause a one-to-two hour delay of melatonin release. Benzodiazepines have also been shown to increase plasma Cortisol and Prolactin concentrations. This may help to explain why long-term use of benzodiazepines can cause menstrual irregularities and pre-menstrual tension in women and breast enlargement in men. Clonazepam may alter insulin secretion after a single dose.
GABA, or gamma-aminobutyric acid, is the most important and widespread inhibitory neurotransmitter in the brain. Excitation in the brain must be balanced with inhibition or anxiety, restlessness, irritability, insomnia and even seizures can occur. GABA are a class of receptors that include GABA-A, GABA-B and GABA-C and although all induce relaxation and sleep, benzodiazepines and most sleeping pills work by strongly accentuating GABA-A because the binding ability is ten times stronger. But GABA-A also counteracts the effects of Melatonin. Neither GABA-B nor GABA-C alters the effects of Melatonin.
Millions of neurons respond to GABA, meaning that it has a general calming influence on the brain and body. Benzodiazepines enhance GABA-A, reducing the brain's output of excitatory neurotransmitters such as Norepinephrine (Noradrenaline), Serotonin and Dopamine. These excitatory neurotransmitters are essential for mental alertness, muscle tone and coordination, memory, emotional responses, endocrine gland secretions, heart rate and blood pressure control – all of which may be impaired by the drug. Other receptors for benzodiazepines that are not governed by GABA-A are in the kidneys, colon, blood cells and adrenal gland. The receptors react to prolonged use of the medications by increasing in number and/or reducing sensitivity to GABA-A.
Benzodiazepines, Alcohol, Barbiturates and Steroids bind to GABA-A, but Benzodiazepines also affect three GABA-A categories including 1) those that mediate sedation and tolerance 2) the hippocampus, striatum, and spinal cord to mediate anti-anxiety activity and spinal cord function; and 3) the peripheral benzodiazepine receptor that are found throughout the body and brain affecting the heart, immune response, steroid synthesis and inflammation (to name a few).
The brain then reduces its own production of GABA, and during a too rapid withdrawal from Benzodiazepines or Sleeping Pills insufficient GABA is present to alleviate the anxiety and over-stimulation. This can result in increased heart rate while sleep decreases as the body and brain are left in a 'flight or fright' response. A gradual reduction allows the GABA-A receptors time to regenerate.
The active peptide in Relax stimulates GABA-A, B and C, providing calming properties without inducing Benzodiazepine side effects that include memory loss, disinhibition, muscle weakness, tolerance or addiction. During the withdrawal process Relax is a welcome tool to combat stress and over-stimulation. And unlike herbs, Relax will not interact with medications.
RELAX is a concentrated peptide found in milk that offers a natural alternative to addictive medications. Scientists from University Henri Poincare-Nancy & Georgetown University Medical Center gathered a group of medical scientists to test the peptide found in milk. They discovered that a milk protein constituent mimicked the action of anxiety reducing drugs but did not trigger any side effects.
- *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, prevent or cure disease or illness. More...
- *Always consult with your healthcare professional before starting any diet, exercise or supplementation program, before taking or stopping any medication, or if you have or suspect you might have any health problem. More...