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Sertraline Success Story - How to wean off Sertraline

Succeed with our Sertraline In-Home Withdrawal and Tapering Program

Zoloft is the trade name for Sertraline.  Sertraline is not considered a drug of abuse but it can cause both physical and psychological dependence. Sertraline is an antidepressant within the SSRI classification, meaning it exerts it action primarily on Serotonin.  Sertraline, like all antidepressants, was approved for short-term use, following studies that lasted approximately 2 months. [1 There is little data on people taking antidepressants for years and time has shown that a Sertraline Discontinuation Syndrome can occur, and can include changes in sleep patterns, an increase in anxiety or depression, gastrointestinal distress and many others. [2] Dependence to Sertraline places extreme demands on your body and nervous system. Point of Return implements slow reduction schedules and specifically designed nutraceuticals to support the body's unique needs during a Sertraline taper. Let our experts help you succeed by guiding you on how to wean off Sertraline with the correct taper rates. We have helped people all over the world and are here to help you too.*

    Dene - Overcoming Sertraline withdrawal symptoms success video

    I am proud of my accomplishment completely and entirely due to you, your team and your program.

    By Dene (USA)


    sertraline weaning  help and success

    Today I am alive and I can hold my beautiful son in my arms because of your help.

    by MAYU (USA)


    Although Sertraline is deemed non-addictive, the pharmaceutical companies that produce Sertraline do state that Sertraline can lead to dependence, tolerance and cause a withdrawal syndrome known as Sertraline Discontinuation Syndrome with Sertraline withdrawal symptoms.  If you have difficulty reducing your dose of Sertraline, that is an indication your nervous system has adapted to the drug. [2] Once Sertraline dependence has occurred, its critical to slowly taper off Sertraline to minimize the symptoms. Many find that even with a gradual taper the Sertraline withdrawal symptoms are debilitating, which is why we implement the use of nutraceuticals to both diminish the withdrawal symptoms and assist in recovery. We can show you how to wean off Sertraline.* 



    Sertraline Withdrawal is a cluster of symptoms that can interfere with all aspects of life.  46% describe Sertraline Withdrawal as severe. [5]  Sertraline Withdrawal is deemed the Sertraline Discontinuation Syndrome and can include irritability, anxiety, nausea, dizziness, nightmares, prickling of the skin, insomnia and many other symptoms. Sertraline withdrawal symptoms can begin by missing one dose or even through a dose reduction. Sertraline withdrawal can be minimized by learning how to wean off Sertraline and including use of nutraceuticals.  Our nonprofit has helped people all over the world, contact us for help to come Sertraline.*


    I am so thankful for the all the supplements I take now from Point of Return, they have eased my suffering!

    by Lori (USA)


    I am so grateful for Point of Return and for all the support I have received to help me to taper from Sertra;ome, which I had been on for about 14 years. The almost immediate replies to emails and arrival of orders was humbling and the wonderful support of the POR team was a great help to me throughout the whole process. I found the slow-tapering programme to be both sensible and doable and have learned so much from undertaking the programme. Thank you so much to all at Point of Return. May God bless you! - Louise (Ireland)



    Our Sertraline At-Home Withdrawal Tapering Program combines a slow Sertraline taper with a powerful holistic approach to minimizing symptoms.  This allows you to step down gently from Sertraline under the close guidance of Our Team, Your Physician, and Pharmacist.  Our Pre-taper is necessary to help provide relief. You do not taper Sertraline until you are feeling better.  Our nonprofit has been helping people all over the world to escape Sertraline and antidepressants dependence for years.  You are not alone through the process.*

    Our areas of expertise are Antidepressants, Benzodiazepines, Sleeping Pills and Painkillers on a case-by-case basis.  Our innovative approach to antidepressant tapering encompasses a holistic method to empower you on your path to recovery. Don't Wean Sertraline alone, work with us.*

    Learn how to wean off Sertraline with Point of Return



    • aggression
    • anxiety
    • balance issues
    • blurred vision
    • brain zaps
    • concentration impairment
    • constipation
    • crying spells
    • depersonalization
    • diarrhea
    • dizziness
    • electric shock sensations
    • fatigue
    • flatulence 
    • flu-like symptoms
    • hallucinations
    • hostility
    • highly emotional
    • indigestion
    • irritability
    • impaired speech
    • insomnia
    • jumpy nerves
    • lack of coordination
    • lethargy
    • migraine headaches / increased headaches
    • nausea
    • nervousness
    • over-reacting to situations
    • paranoia
    • repetitive thoughts or songs
    • sensory & sleep disturbances
    • severe internal restlessness (akathisia)
    • stomach cramps
    • tremors
    • tinnitus (ear ringing or buzzing)
    • tingling sensations
    • troubling thoughts
    • visual hallucinations / illusions
    • vivid dreams
    • speech issues
    • visual changes
    • worsened depression* 

    We get so much from this taper program, the phone chats, emails, all your time for only the price of the nutraceuticals. You can't find this any where else! This program is so amazing because these people have struggled and now dedicate their lives to helping others that are struggling too.

    by Lori (USA)



     Proven Tapering Program completed At-Home

    ✔ Slowly Wean Off Sertraline

    ✔ All-Natural Nutraceuticals to help ease symptoms and make Sertraline Withdrawal more comfortable*

    ✔ Professional information and support to empower you 

    ✔ Free Mentoring on our 24/7 private Discussion Board


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    It is estimated that 20% of people quitting antidepressants will experience withdrawal symptoms, but other studies suggest up to 80% of people who abruptly stop antidepressants may experience withdrawal symptoms.  Sertraline, like all antidepressants, work by altering our natural neurotransmitter production, often shunting Serotonin or Norepinephrine levels higher in the brain while starving other areas of the body. Sertraline withdrawal can be mistaken for depression and the physical complaints not identified.  Tapering Sertraline slowly is necessary to minimize the Sertraline withdrawal symptoms. [4] Generally the first symptoms are felt after either missing a dose or reducing a dosage.  For some the Sertraline withdrawal symptoms are severe, immediately interfering with life, and for others the symptoms are more tolerable. If you want help with how to wean off Sertraline safely, please contact our experts. You can succeed!*

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    I am generally feeling like I have better clarity of thought, my mood is lighter and I have more energy. I truly thank GOD for leading me to your website, not just for myself but also to tell others about Point of Return..


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    Mayu - Sertraline Withdrawal Symptoms Success Stories

    Today I am alive and I can hold my beautiful son in my arms because of Point of Return's help with their withdrawal program and compassion. More...

    Mayu (Sertraline Withdrawal Success Story)

    Karen - How to wean off Sertraline

     To those that are beginning this journey; this process is not a walk in the park, but it's achievable and each testimony is someone who walked through your shoes and overcame! More...

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    Stephen - Sertraline Taper Success Stories

    After spending  virtually all of my adult life on antidepressants, I had often wondered if I’d ever feel as “alive” again. Well, I’m thankful to report today that I’m feeling alive again in ways I haven’t felt since before I began taking antidepressants!  More...

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    Dene - Sertraline Withdrawal Symptoms Help

    I am proud of my accomplishment, completely and entirely due to you, your team and your program. More...

    Dene  (Sertraline Withdrawal Success Story)

    Peggy - Sertraline Weaning help

     I am generally feeling like I have better clarity of thought, my mood is lighter and I have more energy. I truly thank GOD for leading me to your website, not just for myself but also to tell others about Point of Return.. More...

    Peggy (Sertraline Withdrawal Success Story)



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    How to wean off Sertraline anywhere in the world

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      By 2013 Sertraline (Zoloft) was the most prescribed antidepressant and second most prescribed psychiatric medication (Alprazolam was first) on the United States market, with over 41 million prescriptions. 

      New research at Wake Forest Baptist Medical Center found that Sertraline  significantly increased the volume of one brain region in depressed subjects but decreased the volume in two brain areas in other subjects. Both areas in the brain are critical for a wide array of functions including memory, learning, spatial navigation, will, motivation and emotion. 

      Because SSRI's influence numerous systems of the body and brain, stopping Sertraline abruptly can cause a discontinuation syndrome known as withdrawal. 60% of Sertraline patients were found to experience Sertraline withdrawal symptoms. 

      Zoloft's (Sertraline) history dates back to the early 1970s when a scientist named Reinhard Sarges was working on a set of psychoactive compounds called tametraline for Pfizer Pharmaceutical. The initial development brought strange and unwanted side effects in animal tests but in 1977 two other scientists combined tematraline with other compounds and found a Serotonin Reuptake Inhibitor that later became Zoloft (Sertraline). 

      In 1991 Sertraline was officially approved by the FDA and in 2002, Zoloft was approved for use in children and teenagers under the age of 18 (with OCD). In 2005 the FDA added a warning label about Zoloft (Sertraline) advising of suicidal behavior, but in 2007 the warning was revised to include young adults up to the age of 24. By 2013 Zoloft (Sertraline) was the most prescribed antidepressant and second most prescribed psychiatric medication (Alprazolam was first) on the United States market, with over 41 million prescriptions.

      New research at Wake Forest Baptist Medical Center found that Sertraline (Zoloft) significantly increased the volume of one brain region in depressed subjects but decreased the volume in two brain areas in other subjects. Both areas in the brain are critical for a wide array of functions including memory, learning, spatial navigation, will, motivation and emotion. 

      Sertraline is an antidepressant in a group of drugs called Selective Serotonin Reuptake Inhibitors (SSRIs) that exerts the majority of its action on Serotonin, with minimal effects on Norepinephrine and Dopamine. Compared to other SSRIs (Selective Serotonin Reuptake Inhibitors), Sertraline tends to have a higher rate of psychiatric side effects including anxiety, agitation, and insomnia. 

      Serotonin influences the cardiovascular, renal, immune and gastrointestinal systems due to its effect on the contraction of smooth muscles, and is essential to regulate body temperature, heart rate, blood pressure and the sympathetic nervous system. The alteration of Serotonin by Sertraline explains the high rate of gut and cardiovascular related side effects. Patients on Sertraline have much higher rates of sexual dysfunction versus other antidepressants due to Sertraline effect on Serotonin, but lower rates of cognitive decline from its secondary effect on Dopamine. In pregnant women, higher rates of birth defects have been associated with Sertraline due to significant concentrations being present in fetal blood.*

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      Miranda - Sertraline taper Success Story

      “Each day that comes is filled with renewal, increased strength, and a determination to not let my story go unspoken. Thank you, Point of Return, for the great part you have played in my story of healing. I will remain forever grateful.

      —Miranda (Sertraline Withdrawal Success Story)




      The side effects of antidepressants can cause problems at first, but they generally improve with time. 

      It's important to continue treatment, even if you're affected by side effects, as it will take several weeks before you begin to benefit from treatment. With time, you should find that the benefits of treatment outweigh any problems from side effects. 

      During the first few months of treatment, you'll usually see your doctor or a specialist nurse at least once every 2 to 4 weeks to see how well the medicine is working. 

      For more information about your specific medicine, see the patient information leaflet that comes with it.

      SSRIs and SNRIs 

      Common side effects of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) can include: 

      feeling agitated, shaky or anxious, feeling and being sick, indigestion and stomach aches, diarrhoea or constipation, loss of appetite, dizziness, not sleeping well (insomnia), or feeling very sleepy, headaches, loss of libido (reduced sex drive), difficulties achieving orgasm during sex or masturbation, difficulties obtaining or maintaining an erection (erectile dysfunction)

      These side effects should improve within a few weeks, although some can occasionally persist.

      Tricyclic antidepressants (TCAs) 

      Common side effects of TCAs can include: 

      dry mouth, slight blurring of vision, constipation, problems passing urine, drowsiness, dizziness, weight gain, excessive sweating (especially at night), heart rhythm problems (arrhythmia), such as noticeable palpitations or a fast heartbeat (tachycardia).  

      The side effects should ease after a couple of weeks as your body begins to get used to the medicine.


      Severe: visual impairment, coma, seizures, anaphylactoid reactions, bronchospasm, ocular hypertension, suicidal ideation, SIADH, torsade de pointes, AV block, ventricular tachycardia, vasculitis, bradycardia, lupus-like symptoms, agranulocytosis, serum sickness, GI bleeding, pancytopenia, aplastic anemia, Stevens-Johnson syndrome, toxic epidermal necrolysis, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), angioedema, rhabdomyolysis, optic neuritis, pancreatitis, hepatic failure, pulmonary hypertension, renal failure (unspecified), serotonin syndrome, bone fractures, neonatal abstinence syndrome, persistent pulmonary hypertension of the newborn  

      Moderate: ejaculation dysfunction, constipation, palpitations, impotence (erectile dysfunction), melena, ataxia, euphoria, teeth grinding (bruxism), hallucinations, confusion, hypertension, sinus tachycardia, peripheral vasodilation, hypercholesterolemia, bullous rash, blurred vision, elevated hepatic enzymes, edema, hematuria, vaginal bleeding, priapism, hypothyroidism, hyperglycemia, galactorrhea, hypoglycemia, diabetes, dystonic reaction, akathisia, depression, impulse control symptoms, hostility, psychosis, mania, hyponatremia, QT prolongation, bleeding, thrombocytopenia, platelet dysfunction, leukopenia, hematoma, trismus, cataracts, hepatitis, jaundice, urinary incontinence, hyperprolactinemia, osteopenia, withdrawal withdrawal, growth inhibition


      Mild: nausea, diarrhea, insomnia, xerostomia, dizziness, fatigue, drowsiness, tremor, dyspepsia, agitation, hyperhidrosis, libido decrease, vomiting, appetite stimulation, lethargy, hypoesthesia, hyperactivity, syncope, irritability, purpura, epistaxis, maculopapular rash, alopecia, pruritus, urticaria, muscle cramps, arthralgia, tinnitus, mydriasis, yawning, fever, orgasm dysfunction, hyperkinesis, headache, nightmares, anxiet, petechiae, ecchymosis, photosensitivity, malaise, nocturia, gynecomastia, menstrual irregularity, weight loss


      Children, growth inhibition, suicidal ideation

      The safety and efficacy of sertraline have been established in the treatment of obsessive compulsive disorder in children and adolescents 6 to 17 years of age. Two placebo-controlled trials were conducted in pediatric patients with major depression, but the data were not sufficient to support an indication for use. There is a causal relationship between the use of antidepressants, such as sertraline, and the risk of suicidal ideation and behavior in children, adolescents, and young adults (ages 18 to 24 years). Pooled analysis of 24 placebo-controlled trials (n = 4,400) lasting up to 16 weeks in pediatric patients with major depressive disorder (MDD), obsessive compulsive disorder (OCD), or other psychiatric disorders showed a greater risk of suicidality during the first few months of treatment in those receiving antidepressants (SSRIs and others). The average risk of such events on drug was 4% and 2% for placebo; however, no suicides occurred in these trials. Risk for suicidality does not appear to differ among individual antidepressant agents. However, data from a cohort of 36,842 children (age range: 6 to 18 years) suggested those who use multiple antidepressants may have a higher risk of suicide behavior, most likely a result of increased severity of depression rather than drug effect. Suicidal ideation appears to be more prevalent in children with or at high risk for bipolar affective disorder on antidepressants. In a study of 52 patients (mean age: 15 years; range: 7 to 22 years) with bipolar affective disorder or subthreshold manic symptoms, 25.5% had new onset suicidal ideation within the first 3 months of antidepressant use. The clinical need for an antidepressant in children or young adults for any use must be weighed against the risk of increased suicidality; patients who are started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior, particularly within the first few months of starting therapy or after dose changes. It is unknown if the suicidality risk extends to longer-term therapy (i.e., beyond several months). The possibility of a suicide attempt is inherent in patients with primary depressive symptoms or symptoms secondary to another primary disorder such as OCD. All patients with a history of suicidal ideation or behaviors prior to treatment are considered at an increased risk for suicidal ideation or attempts, and should be closely monitored during treatment with sertraline. In patients who exhibit a worsening of depression or emerging suicidality, a decision should be made to change or discontinue treatment. If discontinuing, the medication should be tapered as rapidly as possible, but with recognition that abrupt discontinuation can also cause adverse symptoms. All antidepressants should be prescribed in the smallest quantity consistent with good patient management in order to reduce the risk of overdose. Data are inadequate to determine whether the chronic use of SSRIs causes long-term growth inhibition; however, decreased appetite and weight loss have been observed with the use of SSRIs. Monitor for potential growth inhibition (e.g., weight and height) in pediatric patients treated with an SSRI.   


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      According to the FDA 

      Discontinuation of Treatment with Sertraline 

      Symptoms associated with discontinuation of SERTRALINE and other SSRIs and SNRIs, have been reported (see PRECAUTIONS). Patients should be monitored for these symptoms when discontinuing treatment. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate. 


      Inform pregnant women that SERTRALINE may cause withdrawal symptoms in the newborn or persistent pulmonary hypertension of the newborn. Talk to your healthcare provider about the benefits and risks of taking SERTRALINE during pregnancy.


      *While great care has been taken in organizing and presenting the material throughout this website, please note that it is provided for informational purposes only and should not be taken as Medical Advice. 

      *The statements/info on this website have not been evaluated by the Food and Drug Administration (FDA). The products and labels mentioned / sold are not intended to diagnose, treat, cure, or prevent any disease or illness. 

      *The program outlined in Point of Return is not meant to substitute your doctor, instead it is to be utilized with Your physician to help you with your drug withdrawal process and with his or her consent throughout. 

      *This program is not meant to cure or prevent any disease or illness. 

      *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support throughout the process. More..